Tatsuhiko Matsushita,a,b Tosiaki Miyati,a,b Kazuya Nakayama,a Takashi Hamaguchi,a,c Yoshihiko Hayakawa,d Allen G. Farman,e and Shigeki Ohtakea,b.
a Kanazawa University, Graduate School of Medical Science, Division of Health Science, 5-11-80 Kodatsuno, Kanazawa, 920-0942, Japan
b Kanazawa University, Institute of Medical, Pharmaceutical and Health Science, Wellness Promotion Science Center, 5-11-80 Kodatsuno, Kanazawa, 920-0942, Japan.
c Kanazawa University Hospital, Department of Radiology, 13-1 Takara-machi, Kanazawa, 920-8641, Japan
d Kitami Institute of Technology, Department of Computer Science, Faculty of Engineering, 165 Koen-cho, Kitami, Hokkaido, 090-8507, Japan
e University of Louisville School of Dentistry, Division of Radiology and Imaging Science, Department of Surgical and Hospital Dentistry, Louisville, Kentucky 40292
We developed a novel system for imaging and qualitatively analyzing the surface vessels using near-infrared (NIR) radiation using tuned aperture computed tomography (TACT®). The system consisted of a NIR-sensitive CCD camera surrounded by sixty light emitting diodes (with wavelengths alternating between 700 or 810 nm). This system produced thin NIR tomograms, under 0.5 mm in slice thickness. The venous oxygenation index reflecting oxygen saturation levels calculated from NIR tomograms was more sensitive than that from the NIR images. This novel system makes it possible to noninvasively obtain NIR tomograms and accurately analyze changes in oxygen saturation. © 2011 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.3595424]
Keywords: near infrared; tuned aperture computed tomography; near infraered tomogram; venous oxgenation index.
Paper 10642PR received Dec. 8, 2010; revised manuscript received Apr. 6, 2011; accepted for publication May 9, 2011; published online Jul. 8, 2011